
Best Autoimmune Skin & Vascular Disease Treatment in Hyderabad | Biologics & Surgery
Comprehensive clinical and aesthetic management for Psoriasis, Vitiligo, Scleroderma, Dermatomyositis, Sjögren’s syndrome, and severe Vasculitis. Cosmo Radiance offers targeted biologic infusions, Excimer laser therapy, and advanced surgical melanocyte transfer in a highly sterile, hospital-grade environment.
Elite Medical Remission & Laser Restoration for Autoimmune Skin Diseases
The ultimate multidisciplinary protocol for Psoriasis, Vitiligo, Scleroderma, and Vasculitis. We halt the internal autoimmune attack utilizing advanced biologics and seamlessly restore your skin’s flawless appearance using world-class surgical and laser technology.
Sterile Biologic Infusions | Targeted Excimer Lasers | Class-100 OT Vitiligo Surgery
*Treatment pathways are highly customized based on the specific autoimmune condition, autoantibody profile, and the extent of vascular or systemic organ involvement.
* Clinical management directed exclusively by Senior Dermatologists Dr. Anusha Meka, Dr. Geetha Madhuri Chanda, and Dr. Udaysree Ellori, with surgical interventions by Dr. Prem Sunder Thumu.

Before & After Gallery
Specialists For This Treatment

Dr. Prem Sunder Thum
Director & Consultant Plastic, Reconstructive and Cosmetic Surgeon

Dr. Geetha Madhuri Chanda
Consultant Dermatologist

Dr. Niharika Manne
Consultant Plastic Surgeon

Dr. Anusha Meka
Consultant Dermatologist

Dr. M. Arjun Reddy
Cosmetic & Plastic Surgeon
Why Consider This Treatment
at Cosmo Radiance?
The Unrivaled Hybrid Advantage: Corporate hospitals solely focus on internal medication; generic day clinics only offer superficial creams and basic lasers. Cosmo Radiance provides high-end systemic Biologics AND world-class aesthetic laser and surgical restoration completely under one roof.
01Advanced Surgical Vitiligo Care: We offer exclusive access to Non-Cultured Epidermal Cell Suspension (NCES) and punch grafting, performed meticulously by M.Ch Plastic Surgeons in Class-100 OTs, ensuring the highest repigmentation success rates in India.
02State-of-the-Art Laser Ecosystem: Fully equipped with Targeted UVB/Excimer technology for Psoriasis and Vitiligo, the Candela CO2RE CO2 laser for Scleroderma scar revision, and the Fotona StarWalker for erasing post-inflammatory dark marks left by healed rashes.
03Vasculitis Ulcer Mastery: Utilizing painless Low-Level Laser Therapy (LLLT) and advanced biological matrices to rapidly close and heal necrotic ulcers caused by severe blood vessel inflammation, preventing permanent tissue loss.
04Uncompromising Clinical Sterility: A premium, ultra-clean luxury hospital environment that is absolutely vital for protecting patients whose immune systems are intentionally suppressed by systemic autoimmune therapies.
05Hospital-Grade Infrastructure for Complex Immunology
Class-100 Modular OTs
High-positive pressure, ultra-sterile surgical suites utilized exclusively for delicate Vitiligo cellular grafting and the safe surgical debridement of infected Vasculitis ulcers.
Dedicated Biologic Infusion Suites
Private, closely monitored luxury lounges designed for the safe, stress-free intravenous administration of high-end autoimmune medications.
Precision Laser Lounges
Dedicated clinical rooms specifically optimized with eye-safe protocols for Targeted UVB, Excimer, Fotona StarWalker, and Candela CO2RE fractional laser treatments.
HEPA-Filtered Environment
Integrated HVAC fresh-air systems actively filtering the entire clinic environment to maintain absolute clinical purity and protect deeply immunosuppressed patients.
24/7 Tertiary Care Backup & ICU Facility
Ideal Candidates
Patients suffering from moderate to severe Plaque Psoriasis or active Psoriatic Arthritis seeking highly effective, life-changing Biologic therapies.
Individuals with localized, segmental, or generalized Vitiligo seeking aggressive repigmentation via Targeted UVB lasers or advanced cellular grafting surgery.
Patients formally diagnosed with Connective Tissue Diseases (like Scleroderma or Dermatomyositis) requiring expert systemic autoimmune management combined with laser skin revision.
Those suffering from Rheumatoid Vasculitis or Urticarial Vasculitis experiencing painful palpable purpura, non-healing leg ulcers, or severe blood vessel inflammation.
Patients with Sjögren’s syndrome suffering from severe cutaneous dryness requiring intense medical barrier repair protocols.
Patients whose autoimmune flare has finally subsided, but who are deeply distressed by the resulting post-inflammatory hyperpigmentation (PIH) and textual scarring.
* Final candidacy is determined during a 3D Vectra H2 imaging consultation.
Comprehensive Condition Classification & Treatment Protocols
Papulosquamous (Psoriasis & Psoriatic Arthritis)
The immune system causes rapid epidermal cell buildup, leading to thick, scaly, bleeding plaques and severe joint inflammation. Managed aggressively with targeted Biologics (e.g., IL-17 or TNF-alpha inhibitors) for deep internal remission, paired with Targeted UVB/Excimer lasers to rapidly clear stubborn skin plaques without exposing the entire body to UV radiation.
Pigmentary Destruction (Vitiligo Spectrum)
Autoimmune CD8+ T-cells aggressively destroy melanocytes, causing expanding white patches. Treated medically with potent topical JAK inhibitors and Targeted Excimer Light Therapy to stimulate follicular repigmentation. For Vitiligo that has remained stable for over a year, our M.Ch surgeons perform advanced Non-Cultured Epidermal Cell Suspension (NCES) grafting in our Modular OTs.
Connective Tissue (Scleroderma & Dermatomyositis)
Scleroderma involves massive collagen overproduction causing tight, hardened, restrictive skin. Dermatomyositis presents with severe photosensitive rashes (Heliotrope rash, Gottron's papules) and muscle weakness. Treated with systemic immunosuppressants, vasodilators, strictly controlled photoprotection, and Candela CO2RE fractional CO2 lasers to break down fibrotic tissue and dramatically improve skin pliability.
Vascular Inflammation (Vasculitis & Sjögren’s Syndrome)
Conditions like Rheumatoid Vasculitis or Urticarial Vasculitis cause the actual blood vessels feeding the skin to inflame and necrose, leading to palpable purpura and agonizing, deep skin ulcers. Sjögren’s syndrome causes extreme systemic dryness and cutaneous xerosis. Managed with systemic steroids/biologics, rigorous medical barrier repair, and Low-Level Laser Therapy (LLLT) to hyper-accelerate the healing of open vascular ulcers.
Understanding Autoimmune Cutaneous & Vascular Disorders
Autoimmune skin and vascular diseases occur when the body’s immune system misidentifies its own healthy tissues—specifically the epidermis, dermis, connective tissues, or the blood vessels feeding them—as foreign threats. This results in highly visible, profoundly distressing conditions. Psoriasis and Psoriatic Arthritis cause rapid skin cell hyperproliferation and joint destruction; Vitiligo aggressively destroys melanin-producing cells causing depigmented white patches; Scleroderma triggers extreme collagen overproduction, hardening the skin; Dermatomyositis causes severe photosensitive rashes and muscle weakness; Sjögren’s syndrome attacks moisture-producing glands resulting in severe cutaneous xerosis (dryness); and vascular conditions like Rheumatoid Vasculitis and Urticarial Vasculitis inflame and destroy blood vessels, leading to painful palpable purpura and deep, necrotic skin ulcers. Treating these complex interconnected diseases requires a sophisticated dual approach. At Cosmo Radiance, our clinical dermatologists utilize state-of-the-art Biologics, immunosuppressants, and JAK inhibitors to internally switch off the aggressive immune attack. Simultaneously, we deploy advanced aesthetic interventions—such as Targeted UVB/Excimer lasers for Vitiligo repigmentation, Low-Level Laser Therapy (LLLT) for Vasculitis ulcers, and the Candela CO2RE CO2 laser to break down Scleroderma fibrosis—to completely restore your physical appearance and quality of life.
Types of Treatment
- Top RecommendedTargeted Biologics & JAK InhibitorsGold Standard
- Top RecommendedTargeted UVB / Excimer TherapyGold Standard
- Top RecommendedVitiligo Melanocyte Surgery (NCES)Gold Standard
- Candela CO2RE® Scar & Tissue Revision
Cosmo Radiance vs. Corporate Hospitals & Generic Day Clinics
Why settle for standard when you can have high-definition?
Total Treatment Scope
VSCosmo Radiance (Hybrid Clinical & Aesthetic Center)
Only Internal Medicine OR Only Superficial Lasers
Corporate Rheumatology / Generic Day Clinics
Systemic Biologics + Advanced Laser + Surgical Restoration
Advanced Vitiligo Management
VSCosmo Radiance (Hybrid Clinical & Aesthetic Center)
Basic topical steroid creams; highly limited or no surgical capability
Corporate Rheumatology / Generic Day Clinics
Targeted UVB Lasers & M.Ch Surgical Melanocyte Transfer (NCES)
Post-Flare Aesthetic Restoration
VSCosmo Radiance (Hybrid Clinical & Aesthetic Center)
Completely ignored; patients are discharged and left with permanent, highly visible scars
Corporate Rheumatology / Generic Day Clinics
Candela CO2RE & Fotona StarWalker for 100% Scar & Pigment Clearance
Vasculitis Ulcer Care
VSCosmo Radiance (Hybrid Clinical & Aesthetic Center)
Basic gauze dressings, iodine, and waiting for extremely slow, painful natural healing
Corporate Rheumatology / Generic Day Clinics
LLLT Laser Healing, Biological Dressings & Class-100 OT Surgical Debridement
Patient Care Environment
VSCosmo Radiance (Hybrid Clinical & Aesthetic Center)
Crowded, stressful general hospital wards with incredibly high infection cross-contamination risks
Corporate Rheumatology / Generic Day Clinics
Private, Luxury Lounges & Highly Sterile HEPA-Filtered Environments
Advanced Technology

Targeted Biologics + Excimer/UVB Lasers + Candela CO2RE® CO2 Laser + NCES Grafting
- Targeted Systemic Biologics: Elite, highly specific injectable medications (like Secukinumab or Adalimumab) that block the exact inflammatory pathways causing Psoriasis, Psoriatic Arthritis, and severe Vasculitis.
- Targeted UVB / Excimer Light Therapy: The global clinical gold standard for stimulating dormant melanocytes in Vitiligo and rapidly clearing extremely stubborn Psoriasis plaques without exposing healthy skin to UV radiation.
- Candela CO2RE® Fractional CO2 Laser: The most advanced resurfacing laser available. Utilized aggressively by our experts to break down hardened, fibrotic tissue in Scleroderma and to vaporize severe textural scarring left by healed vasculitis ulcers.
- Melanocyte Transfer Surgery (NCES): Advanced cellular grafting where healthy pigment cells are harvested from a hidden donor site, suspended in a solution, and transplanted into stable Vitiligo patches by our M.Ch Plastic Surgeons.
- Fotona StarWalker® Q-Switched Laser: Safely and permanently shatters and clears the intense post-inflammatory hyperpigmentation (PIH) that invariably follows the healing of autoimmune skin flares and rashes.
The Cosmo Radiance
Clinical Advantage
Deep Internal Medical Remission
Our clinical dermatologists utilize the latest Biologics, JAK inhibitors, and steroid-sparing immunosuppressants to rapidly halt the internal autoimmune attack, stopping the progression of the disease and joint destruction at the cellular level.
Targeted Laser Repigmentation & Clearance
For Vitiligo and Psoriasis, we don't just rely on slow-acting creams. We use highly concentrated Targeted UVB/Excimer light to forcefully stimulate pigment production and clear thick inflammatory plaques exponentially faster than traditional therapies.
Surgical Aesthetic Restoration
When medical therapy isn't enough to repigment stable Vitiligo, our M.Ch Plastic Surgeons step in. They perform highly intricate cellular grafting (NCES) in our Modular OTs to permanently and flawlessly restore your natural skin color.
Advanced Vascular Ulcer Healing
Vasculitis can cause blood vessels to die, leaving agonizing, deep open ulcers on the legs and body. We immediately deploy Low-Level Laser Therapy (LLLT) and advanced biological matrices to hyper-accelerate tissue repair and prevent severe permanent scarring.
Preparation Tips
- 01
Bring all previous blood work, comprehensive ANA (Antinuclear Antibody) panels, skin biopsy reports, Direct Immunofluorescence (DIF) results, and your complete medical history to your initial diagnostic consultation.
Pre-Op Requirement - 02
For Vitiligo patients considering NCES surgery, your condition must be clinically stable (absolutely no new white patches, and no expansion of existing patches) for a minimum of 6 to 12 months.
Pre-Op Requirement - 03
Strictly adhere to advanced, medical-grade sun protection protocols (SPF 50+ applied every 2 hours), as many autoimmune skin conditions, particularly Dermatomyositis and Lupus, are severely photo-aggravated and triggered by UV exposure.
Pre-Op Requirement
Recovery & Aftercare
Intensive Medical-Grade Barrier Repair
MandatoryOngoing Maintenance Light & Laser Therapy
MandatoryRigorous Systemic Medical Monitoring
Long-Term Results
Profound, long-term clinical remission of thick Psoriasis plaques and severe joint inflammation, allowing patients to return to a completely normal, active, and pain-free life.
Significant, and very often total, repigmentation of stable Vitiligo patches via advanced surgical grafting and targeted light therapy, dramatically restoring patient confidence.
Arrested progression of Scleroderma skin hardening, with visibly improved skin pliability, elasticity, and texture achieved through fractional CO2 laser intervention.
Complete, rapid closure of dangerous vascular ulcers and a massive reduction in the dark, pigmented scarring typically caused by healed vasculitis and dermatomyositis flares.
Combination Procedures
Biologics + Targeted UVB Therapy: The ultimate one-two punch for severe, whole-body Psoriasis. Systemic biologics rapidly shut down the internal inflammation and joint pain, while targeted light therapy instantly clears the visible, embarrassing skin plaques.
Medical Stabilization + Melanocyte Grafting: The definitive protocol for Vitiligo. We first use oral and topical medical therapies to stop the disease from spreading (achieving stabilization), followed by M.Ch surgical NCES grafting to perfectly repigment the remaining white patches.
LLLT Wound Care + Candela CO2RE Resurfacing: A sequential, highly effective protocol for severe Vasculitis. We first heal the deep, open ulcers using pain-free cold laser therapy, and once healed, use the CO2RE fractional laser to aggressively erase the resulting restrictive scar tissue.
Non-Surgical Alternatives
Risks & Complications
Increased susceptibility to minor bacterial or viral infections while on systemic immunosuppressants or biologics, which is strictly monitored and managed via regular, mandatory blood panels by our clinical team.
In Vitiligo surgery, there is a small inherent risk of graft failure, cobblestoning, or uneven repigmentation. This risk is heavily mitigated by our M.Ch surgeons' vast microsurgical expertise and our Class-100 OT sterile environment.
Severe post-inflammatory hyperpigmentation (PIH), a nearly unavoidable byproduct of intense cutaneous inflammation. This is proactively planned for and cleared by our aesthetic team using the Fotona StarWalker once the active disease is controlled.
Immunosuppressed Patient Safety: 100% NMC Compliant Infrastructure
Sterile Biologic Administration
High-end infusions for severe Plaque Psoriasis or Urticarial Vasculitis are conducted in highly monitored, active HEPA-filtered suites to eliminate airborne pathogens.
Aseptic Surgical Fields
Advanced cellular grafting (Non-Cultured Epidermal Cell Suspension) for Vitiligo and surgical debridement of Vasculitis ulcers are performed exclusively in our Class-100 Modular OTs.
In-House ICU Capability
For rare, acute flares of systemic vasculitis requiring intensive medical stabilization and high-dose IV steroids, our in-house 3-bed ICU provides 24/7 critical, life-saving monitoring.
Integrated Systemic Care
Seamless, real-time collaboration between our elite dermatologists and supporting rheumatological pathways to monitor organ health, liver function, and joint integrity safely.
India's Premier Multidisciplinary Hospital for Complex Autoimmunity
Patients suffering from complex conditions like Psoriatic Arthritis, Dermatomyositis, or Rheumatoid Vasculitis often experience fragmented care, bouncing endlessly between rheumatologists who ignore the aesthetic damage, and generic day clinics that lack the medical infrastructure to safely prescribe potent systemic medications. Cosmo Radiance completely bridges this critical gap within our premium 15,000 sq. ft. surgical hospital in Miyapur. We offer a true 360-degree clinical ecosystem: from highly sterile, HEPA-filtered infusion suites for biologic administration, to dedicated Excimer and Q-Switched laser lounges, all the way to our Class-100 Modular OTs where our Board-Certified M.Ch Plastic Surgeons perform highly intricate Melanocyte Transfer (NCES) surgeries for stable Vitiligo.
Hospital-Grade Surgical Infrastructure
Treatment Investment
Starting Estimate
Pricing starts at just ₹1,000 for a comprehensive diagnostic and rheumatological consultation. Targeted UVB/Excimer laser therapies start from ₹2,000 per session. Complex, life-changing interventions—including Biologic infusions, severe Vasculitis wound management, and Class-100 OT Vitiligo NCES grafting—are custom-quoted based on the exact clinical scope. 0% EMI financing is readily available to ensure uninterrupted access to premium care.
*Final cost depends on BMI grading, treatment zones, and clinical complexity.
Frequently Asked Questions
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