Advanced NAD+ & PLA Cellular Therapy for Rejuvenation in Hyderabad
Cosmo Radiance offers advanced longevity-medicine in Hyderabad, performed exclusively by clinical longevity physicians in hospital-grade, sterile operating suites. This integrated approach combines NAD+ cellular infusion with PLA biostimulation for natural, long-lasting rejuvenation.
Individual results may vary. A medical consultation is required to determine suitability for treatment.
* All treatments are performed under the direct supervision of Board-Certified MD specialists at Cosmo Radiance, Miyapur, Hyderabad.
Clinical Snapshot
Procedure At-A-Glance
Class-100 Modular OT Verified
Advanced NAD+ & PLA Cellular Therapy for Rejuvenation in Hyderabad at Cosmo Radiance Hyderabad is planned and performed exclusively by board-certified specialists in hospital-grade Class-100 modular operating suites, strictly complying with National Medical Commission (NMC) safety and ethical guidelines.
Precision longevity-medicine with Gold-Standard Clinical Care
At Cosmo Radiance Hyderabad, our longevity-medicine protocol unites specialist medical expertise with advanced clinical infrastructure. Performed exclusively by Clinical Longevity Physicians & Aesthetic Specialists, every procedure utilizes coenzyme NAD+ infusions and Poly-L-Lactic Acid (PLA) biostimulators in registered Class-100 modular operating theatres with dedicated post-procedure care.
Planned and performed exclusively by Clinical Longevity Physicians & Aesthetic Specialists with zero technician delegation
Utilizes authentic coenzyme NAD+ infusions and Poly-L-Lactic Acid (PLA) biostimulators ensuring exceptional precision and safety
Conducted in hospital-grade Class-100 modular laminar flow operating suites
Comprehensive pre-procedure clinical assessment and personalized treatment staging
Structured post-procedure follow-up and accelerated recovery protocols
"Where board-certified specialist precision meets authentic medical technology for predictable, natural patient transformations."
Clinical Outcomes
Our protocol is grounded in evidence-based practice, with patients reporting meaningful improvements in vitality and skin quality. Highly precise outcomes are achieved through individualised MD-supervised care.
Clinical statistics reflect aggregate outcomes; individual results may vary.
Figures shown are based on internal clinical data and do not constitute a promise or guarantee of specific results. Outcomes depend on individual patient factors. All procedures are performed by qualified medical professionals in compliance with NMC guidelines.
Aesthetic Benefits
Gradual, natural-looking restoration of facial volume.
Progressive structural thickening of the dermal matrix.
A refreshed, more luminous skin appearance.
Gradual softening of deeper facial lines and folds.
Long-lasting structural improvement through collagen neogenesis.
Medical Benefits
Clinically supported improvement in fatigue symptoms through mitochondrial support.
Clinical Improvement
Reported improvement in cognitive clarity and mental focus.
Clinical Improvement
Support for DNA repair mechanisms and metabolic health.
Clinical Improvement
Comprehensive 'inside-out' approach to systemic and structural ageing.
Early Mitochondrial Decline (Mild Fatigue & Early Hollowing)
Presenting in the early 30s. Highly subtle flattening of the mid-face coupled with afternoon energy crashes and early 'brain fog'. Clinically best treated with a conservative 1-Vial PLA induction and a 500mg NAD+ infusion to kickstart cellular optimization.
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Type II
Moderate Metabolic & Structural Collapse
Highly visible hollowing in the temples, prominent smile lines, and persistent, daily systemic fatigue. Medically requires a targeted, 2-Vial PLA structural lift synchronized with multi-session, high-dose NAD+ infusions.
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Type III
Severe Pan-Facial Deflation & Executive Burnout
Profound, widespread loss of facial fat pads, extremely hollow temples, and severe, debilitating chronic fatigue heavily impacting daily function. Medically requires a comprehensive, multi-session Full-Face CHPP Longevity Protocol.
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How Does the NAD+ & PLA Cellular Synergy Work?
This integrated protocol combines two clinically established medical interventions—Nicotinamide Adenine Dinucleotide (NAD+) and Poly-L-Lactic Acid (PLA)—to address cellular ageing from both a systemic and structural perspective. NAD+ IV therapy replenishes a vital coenzyme crucial for mitochondrial function, supporting cellular energy production and DNA repair. Concurrently, PLA biostimulator injections stimulate the body's natural collagen production, gradually restoring facial volume and improving skin quality from within. This dual 'inside-out' approach offers a comprehensive strategy for rejuvenation, with results that develop progressively. Administered under full MD supervision at our Miyapur clinic, the protocol is tailored to each patient's unique cellular and aesthetic profile.
Target Areas
Systemic Cellular Grid (Mitochondria)Massive Upregulation of Whole-Body ATP & Brain Function
Mid-Face & Zygomatic Arch (Cheeks)Profound Structural Volumization via PLA
Temporal Fossa (Temples)Correction of Severe Upper Face Hollowing
Nasolabial & Marionette FoldsDeep Structural Erasure of Aging Shadows
Neuro-Cognitive Pathways
Types of Treatment
Top RecommendedThe Ultimate CHPP Longevity Protocol
Gold Standard
Top RecommendedHigh-Dose NAD+ Neuro-Restoration IV
Gold Standard
Top RecommendedTargeted Mid-Face PLA Structural Lift
Gold Standard
Basic Med-Spa Facials vs. Cosmo Inside-Out Longevity
Why settle for standard when you can have high-definition?
Clinical Feature
Unregulated Anti-Aging Spa
Cosmo Radiance NAD+ & PLA Protocol
Mechanism of Action
Strictly Superficial (Topical creams and generic HA fillers)
Profound Inside-Out Biological Synergy (Mitochondrial ATP + Structural Collagen)
Legal Compliance & Safety
Highly Illegal 'Fast-Push' IVs by Unqualified Staff
Injectable biostimulatory micro-particles triggering deep dermal neocollagenesis.
Clinical Advantage / USP
Structural tissue remodeling and volumization.
Direct Patient Result
Restores facial volume and skin tightness from within.
Cosmo Radiance Gold-Standard Protocol#02
The Cosmo Radiance Clinical Advantage
Sequenced Biological Synergy
NAD+ replenishment supports cellular health, creating an ideal environment for PLA to stimulate collagen effectively.
Precision Protocol
Our integrated approach ensures a comprehensive rejuvenation strategy tailored to your profile.
Advanced Delivery Techniques
Micro-cannula techniques enhance comfort and reduce the risk of bruising.
Medical Oversight
All procedures are performed within our registered facility, ensuring clinical accountability.
Preparation Tips
01
Discontinue NSAIDs and high-dose vitamin E for 72 hours prior, subject to physician approval.
Pre-Op Requirement
02
Maintain good hydration in the days leading up to your session.
Pre-Op Requirement
03
Arrive having eaten a light meal to support comfort during IV infusion.
Pre-Op Requirement
04
Bring a full list of current medications and supplements to your consultation.
Pre-Op Requirement
Procedure Steps
01
1. Exhaustive Metabolic & Volumetric Mapping
The MD Specialist rigorously analyzes your systemic blood panel for cellular senescence markers while utilizing Vectra H2 3D imaging to calculate highly precise, mathematical PLA vial requirements.
02
2. Pre-Treatment Hydration & IV Cannulation
Our ICU-certified nursing staff meticulously checks your vitals and painlessly inserts an ultra-fine IV cannula, initiating the highly controlled, 2-hour systemic physiological NAD+ slow-drip.
03
3. Facial Anesthesia & Asepsis
While you relax during the IV infusion, rigorous hospital-grade facial sterilization is performed, followed by the application of high-strength medical topical anesthetic cream to ensure absolute comfort.
04
4. Precision Blunt-Cannula PLA Delivery
Fueled by the active NAD+ infusion, the MD specialist meticulously administers the hydrated PLA matrix deep into the facial sub-dermal plane utilizing ultra-fine micro-cannulas.
05
5. Clinical Verification & 5-5-5 Protocol
Exact pharmaceutical batch numbers are legally recorded in the EMR. A rigorous post-injection massage is performed, and you are strictly discharged with detailed metabolic and 5-5-5 anatomical aftercare mandates.
Recovery Timeline
Immediate Post-Op (Days 1-2)
You will instantly feel a massive, profound surge in neuro-cognitive clarity and systemic energy from the NAD+. Physically, the face will look 'full' due to the PLA carrier water swelling.
Milestone
Days 3-7 (The Deflation Phase)
The PLA sterile water is safely excreted, and facial volume temporarily returns to baseline. Your systemic NAD+ energy levels remain highly elevated, drastically reducing daily fatigue.
Milestone
Weeks 4-6 (Collagen Neo-genesis)
Fueled by the massive cellular ATP reserves, the PLA microparticles aggressively stimulate your fibroblasts. You will highly gradually notice a beautifully natural firming and structural lifting.
Milestone
Month 3+ (Peak Biological Efficacy)
The absolute full, peak biological collagen matrix is successfully established. The face looks profoundly rejuvenated, and chronic systemic senescence (aging) has been significantly reversed.
Milestone
Recovery & Aftercare
Strict 5-5-5 Massage Protocol
Mandatory
You must absolutely and aggressively massage the PLA-treated anatomical zones for exactly 5 minutes, 5 times a day, for 5 consecutive days to definitively ensure the particles are evenly distributed.
Duration: 5 Days
Aggressive Systemic Hydration
Mandatory
Actively consume 3-4 liters of water for 48 hours post-infusion to heavily assist the cellular matrix in safely utilizing the new NAD+ coenzymes and maximizing mitochondrial output.
Duration: 48 Hours
Avoid Extreme Cardiovascular Strain
Mandatory
Strictly avoid all vigorous cardiovascular exercise and heavy lifting for exactly 48 hours to prevent severe vascular flushing and localized PLA swelling.
Duration: 48 Hours
Long-Term Results
Structural volume improvements typically maintained for 24-36 months.
Sustained improvements in energy and clarity with periodic maintenance.
Progressive improvement in skin texture over 3-6 months.
Long-term outcomes supported by healthy lifestyle factors.
Synergistic Combination Procedures
Multi-Modality Protocols for Enhanced & Accelerated Outcomes
Transient, highly mild chest tightness or abdominal cramping specifically during the active NAD+ infusion (Instantly and entirely mitigated by our ICU nurses simply slowing the drip rate).
Highly temporary, localized edema (swelling) specifically at the PLA injection sites, due to the high volume of sterile hydration water utilized (completely resolves within 48 hours).
Highly minor, localized bruising or petechiae (Heavily minimized by our advanced blunt-tip cannula technique and AccuVein mapping).
Sub-clinical micro-nodule formation from PLA. This is almost entirely eliminated by our strict 24-hour PLA pre-hydration protocol and your strict adherence to the 5-5-5 massage rule.
Regulatory Compliance
Clinical Safety Standards We Adhere To
NAD+ is administered as a regulated pharmacological coenzyme requiring documented pre-infusion screening and MD prescription.
All injectable therapies, including PLA biostimulators, are performed exclusively by qualified medical doctors.
Stringent aseptic technique and sterile, single-use equipment are used, maintaining an extremely low infection risk.
Clinically Rigorous Longevity Medicine at Cosmo Radiance, Miyapur, Hyderabad
Cosmo Radiance is a registered medical facility in Miyapur, Hyderabad, equipped with modular clinical suites and a dedicated team of Board-Certified MD specialists.
Hospital-Grade Surgical Infrastructure
Signature Branding Wall
The illuminated Cosmo Radiance insignia wall, reflecting the clinic's modern aesthetic and commitment to transformation.
Touchless Automated Entry
Grand entrance featuring ASSA ABLOY automatic sensor doors, ensuring a hygienic, touch-free, and accessible welcome.
Parametric Reception Artistry
A stunning parametric wooden reception desk that blends architectural art with clinical precision, welcoming guests in style.
Branding & Interior Detail
Close-up of the signature parametric design and Cosmo Radiance branding, reflecting a commitment to aesthetic excellence.
AI Skin Analysis & Pharmacy
A holistic skin health zone featuring advanced AI complexion analysis and a pharmacy stocked with premium brands like Obagi and Uriage.
Designer Reception & Lounge
Sophisticated reception desk and premium waiting lounge featuring modern parametric ceiling design and comfortable seating.
Architectural Landscaped Entrance
A tranquil outdoor waiting lounge and entrance featuring therapeutic landscaping and natural orchids for a healing environment.
Rooftop Terrace Lounge
A serene open-air terrace garden with a water feature, offering a peaceful retreat for patients and visitors.
Individual Privacy Booths
Secluded waiting areas designed with acoustic privacy shields to ensure confidentiality and comfort for every patient.
Pure Air Waiting Lounge
A health-first waiting environment integrated with advanced air purifiers and fresh-air technology for a pollutant-free experience.
Private Waiting Booths
Individualized waiting booths with frosted privacy shields, offering a discreet and comfortable environment for every patient.
Hygienic Smart Washrooms
Premium gender-neutral washrooms equipped with touch-free sensor taps and antimicrobial surfaces for superior hygiene.
OPD Block Entrance
Main entrance to the Out-Patient Department (OPD), designed for easy accessibility and smooth patient navigation.
Modern Clinical Corridors
Spacious, well-lit corridors connecting consultation suites to the billing and administrative zones, designed for seamless patient flow.
Educational Waiting Zone
Comfortable waiting lounges featuring digital screens that provide patient education and treatment insights.
Surgeon Consultation Suite
Executive consultation room equipped with Vectra H2 3D body simulation technology and international surgical accreditations.
Vectra H2 3D Workstation
Dedicated 3D imaging station featuring the Vectra H2 camera system for realistic pre-surgical body and face simulations.
Senior Consultant Cabin
Ergonomically designed private consultation cabin for in-depth discussions with senior specialists. Equipped with sterile trays for precise injectable treatments.
VIP Waiting Lounge
Exclusive VIP lounge featuring plush seating, vertical green gardens, and a private atmosphere for discerning clients.
Procedure Wing & Safety
Sterile procedure wing connecting treatment suites, equipped with integrated fire safety systems and a dedicated nursing station.
Emergency Backup
Immediate access to our on-site ICU and crash cart support, providing an absolute safety net during all injectable procedures.
Hyderabad Center of Excellence & Executive Care
Serving Discerning Patients Across Hyderabad & Worldwide
Conveniently situated in West Hyderabad with signal-free Outer Ring Road (ORR) access from Jubilee Hills, Gachibowli, and the International Airport for Advanced NAD+ & PLA Cellular Therapy for Rejuvenation in Hyderabad.
Luxury Catchment18–22 mins
Jubilee Hills & Banjara Hills
Direct via Road No. 36 / 45 & Inorbit Express Corridor
Via Outer Ring Road (ORR) Exit 3 with seamless 4-lane access
Global Patient Desk35–40 mins
RGIA Airport (NRI & Outstation Guests)
Non-stop expressway via PVNR Elevated Expressway & ORR
Discreet VIP Patient Privacy
Dedicated private consultation lounges, confidential documentation, and discreet back-door surgical discharge for high-profile patients and executives.
Class-100 Laminar Flow OTs
Hospital-grade positive-pressure surgical theatres with continuous HEPA filtration, dedicated full-time MD Anesthesiologists, and emergency critical care backup.
Valet Parking & Secure Access
Underground valet parking with private elevator access directly to our 5th-floor aesthetic surgical suite for effortless arrival and departure.
Dual-Track Financial Options
Transparent pricing with 0% interest EMI options (Bajaj / HDFC) and dedicated cashless insurance TPA desk for reconstructive cases, with zero hidden hospital fees.
Planning Your Visit or Traveling from Out of Town?
Speak directly with our Executive Patient Coordinator for priority slotting, valet assistance, or virtual 3D simulations.
In strict compliance with National Medical Commission (NMC) directives, surgical and dermatological consultations are conducted directly by qualified M.Ch/DNB Plastic Surgeons and MD Dermatologists.
Transparent Medical Investment
Treatment Investment & Care Tiers
Zero hidden fees • Board-certified doctors • Class-100 Modular OT hospital safety
Hospital-Grade Class-100 Modular OT
Clinical EssentialTargeted Care
Standalone High-Dose NAD+ Neuro-Restoration IV
Targeted medical protocol performed by board-certified specialists with uncompromising hospital sterility.
Starting Investment
₹10,000 – ₹20,000INR*
0% Interest EMI: From ₹3,750/mo
Specialist-Led: Performed directly by Board-Certified MD Dermatologist or Specialist
Transparent Pricing: NAD+ & PLA Longevity in Hyderabad
Clinical, CDSCO-compliant precision benchmarks for 2026. 0% EMI available.
Longevity Protocol / Clinical Intervention
Estimated Price Range
Estimated Clinical Dosage & Details
Standalone High-Dose NAD+ Neuro-Restoration IV
₹10,000 – ₹20,000
Typically 500mg - 1000mg (2 to 4 hour ICU-monitored slow drip for severe fatigue)
Standalone PLA Cellular Rejuvenation (Per Vial)
₹35,000 – ₹45,000
Typically 1 Vial (Deep structural pan-facial collagen synthesis)
The Ultimate CHPP Synergy (NAD+ IV + 1 PLA Vial)
₹45,000 – ₹60,000
The highly synergistic protocol: Systemic mitochondrial energy supercharging dermal volume.
Comprehensive Pan-Facial Longevity Package
₹1,20,000 – ₹1,50,000+
Highly discounted: Includes 3 NAD+ IV sessions and 3-4 PLA Vials over a 12-week induction.
Standalone High-Dose NAD+ Neuro-Restoration IV
₹10,000 – ₹20,000
Typically 500mg - 1000mg (2 to 4 hour ICU-monitored slow drip for severe fatigue)
Standalone PLA Cellular Rejuvenation (Per Vial)
₹35,000 – ₹45,000
Typically 1 Vial (Deep structural pan-facial collagen synthesis)
The Ultimate CHPP Synergy (NAD+ IV + 1 PLA Vial)
₹45,000 – ₹60,000
The highly synergistic protocol: Systemic mitochondrial energy supercharging dermal volume.
Comprehensive Pan-Facial Longevity Package
₹1,20,000 – ₹1,50,000+
Highly discounted: Includes 3 NAD+ IV sessions and 3-4 PLA Vials over a 12-week induction.
* Your exact, highly transparent final cost depends entirely and objectively on your specific baseline metabolic deficit, deep tissue lipoatrophy, and the precise mathematical dosage clinically prescribed. Standard combined session pricing starts securely at ₹45,000. Comprehensive, highly discounted multi-session packages for total biological overhaul are heavily recommended and readily available. Easy 0% EMI financing options are provided. Statutory taxes apply.
Frequently Asked Questions
Procedure investment at Cosmo Radiance in Hyderabad is customized based on individual anatomical requirements, treatment complexity, and technology used. We maintain transparent hospital fee structures with 0% EMI financing options.
NAD+ (Nicotinamide Adenine Dinucleotide) cellular therapy involves administering NAD+ to support cellular repair, energy production, and overall cellular function, contributing to rejuvenation.
PLA (Poly-L-lactic Acid) cellular therapy utilizes micro-injections of PLLA to stimulate the body's natural collagen production, improving skin volume and texture over time.
NAD+ therapy can support energy levels and cellular health, while PLA therapy is primarily used for facial volume loss and skin rejuvenation, addressing signs of aging.
When performed by qualified medical professionals in a clinical setting, both NAD+ and PLA cellular therapies are generally considered safe with minimal risks. Consultation is essential.
Administering systemic coenzyme infusions and deep structural biostimulators requires a level of medical infrastructure and clinical oversight that goes beyond what a standard aesthetic clinic can provide. Cosmo Radiance is a registered 15,000 sq. ft. medical facility in Miyapur, Hyderabad, equipped with Class-100 clinical suites, on-site ICU backup, and a team of Board-Certified MD Specialists and ICU-certified nursing staff. All procedures are conducted in full compliance with NMC and CDSCO guidelines, using authenticated, cold-chain-verified pharmaceutical agents — and every session is documented in a formal Electronic Medical Record.
The clinical rationale for combining these two therapies is rooted in cellular biology. PLA biostimulators work by triggering fibroblast activity to produce new collagen — a process that is metabolically energy-intensive. Because NAD+ is a key coenzyme in mitochondrial ATP (energy) production, administering the NAD+ infusion prior to the PLA injection is intended to support fibroblast metabolic capacity at the time of biostimulation. The two treatments also address complementary aspects of ageing: NAD+ supports systemic energy and cognitive function, while PLA addresses structural facial volume loss — making them a logical pairing for patients seeking a comprehensive approach.
These side effects are associated with rapid administration of NAD+ — a practice sometimes seen in unregulated settings where the infusion is delivered too quickly. NAD+ is a potent metabolic activator, and pushing it rapidly into the bloodstream can cause transient cardiovascular and gastrointestinal discomfort. At Cosmo Radiance, all NAD+ infusions are administered via a carefully titrated slow-drip protocol spanning two to four hours, under continuous monitoring by ICU-certified nursing staff. This approach is specifically designed to minimise the risk of these side effects while supporting optimal absorption and patient comfort throughout the session.
PLA biostimulation works through a gradual biological process rather than providing immediate volume. After the initial swelling from the carrier fluid subsides — typically within a few days — the PLA microparticles begin stimulating fibroblast activity and collagen production over the following weeks. Visible structural improvement in facial volume and skin quality generally becomes apparent between six and eight weeks post-injection, with the most pronounced results typically observed at the two-to-three-month mark. Improvements from the NAD+ infusion — such as increased energy and improved cognitive clarity — may be noticed more quickly, often within the first few days following treatment.
The number of sessions required varies between individuals and is determined during your initial medical consultation based on your clinical assessment, degree of facial volume loss, and systemic health goals. As a general clinical guide, an induction course typically involves three to four NAD+ IV infusions spaced approximately one week apart, paired with two to three PLA biostimulator sessions spaced four to six weeks apart. Once the initial course is complete, maintenance requirements are generally infrequent — your treating MD will advise on an individualised maintenance schedule based on your response to treatment.
Oral NAD+ precursors — such as NMN or NR — can support NAD+ levels over time and are a reasonable option for general daily maintenance. However, they are not equivalent to intravenous administration for the purpose of achieving a significant, rapid increase in systemic NAD+ levels. When taken orally, these compounds are subject to digestive breakdown and hepatic first-pass metabolism, which substantially reduces the proportion that reaches systemic circulation. Intravenous delivery bypasses the gastrointestinal tract entirely, allowing the full dose to enter the bloodstream directly. Your treating physician can advise on whether IV therapy, oral supplementation, or a combination of both is appropriate for your individual health goals.
The post-treatment massage protocol — typically involving gentle massage of the treated areas for five minutes, five times a day, for five days — is an important part of the PLA aftercare process. PLA microparticles are deposited in the sub-dermal layer, and regular massage helps ensure they remain evenly distributed as the carrier fluid is absorbed. If the massage protocol is not followed, there is an increased risk that PLA particles may cluster together, potentially forming small, palpable nodules beneath the skin surface. These are generally manageable but are best avoided through consistent adherence to the aftercare instructions provided by your treating physician.
Cosmo Radiance provides itemised, upfront cost breakdowns for all treatment components before any procedure is agreed upon. Your MD Specialist will calculate the specific NAD+ dosage and PLA vial quantity required based on your clinical assessment — you will not be presented with a single opaque package price. All pharmaceutical vials are factory-sealed and opened in your presence during the session, and batch numbers are recorded in your medical record. Flexible 0% EMI payment options are available to make the treatment accessible to patients across Hyderabad without financial pressure.
At Cosmo Radiance, our longevity-medicine is performed exclusively by Clinical Longevity Physicians & Aesthetic Specialists using coenzyme NAD+ infusions and Poly-L-Lactic Acid (PLA) biostimulators. Every treatment is customized to your exact anatomical requirements in our hospital-grade facility, ensuring natural, long-lasting results and maximum patient safety.
Yes. All devices and consumables used at Cosmo Radiance carry rigorous US-FDA Approved, European CE Mark 0120, Swiss/German Liposomal Standards. Every procedure is performed by Senior MD Physicians & Clinical Metabolic Specialists within sterile Class-100 modular environments to ensure complete patient safety.
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